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Fumiaki Koizumi Selected Research

8- (6- methoxypyridin- 3- yl)- 3- methyl- 1- (4- piperazin- 1- yl- 3- trifluoromethylphenyl)- 1,3- dihydroimidazo(4,5- c)quinolin- 2- one

6/2014Synergistic anti-tumor effects of a novel phosphatidyl inositol-3 kinase/mammalian target of rapamycin dual inhibitor BGT226 and gefitinib in non-small cell lung cancer cell lines.

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Fumiaki Koizumi Research Topics

Disease

35Neoplasms (Cancer)
11/2022 - 03/2003
9Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
04/2018 - 03/2003
8Lung Neoplasms (Lung Cancer)
01/2019 - 07/2006
6Neoplasm Metastasis (Metastasis)
11/2022 - 03/2003
5Stomach Neoplasms (Stomach Cancer)
11/2022 - 06/2005
5Colorectal Neoplasms (Colorectal Cancer)
05/2014 - 07/2003
3Breast Neoplasms (Breast Cancer)
03/2016 - 02/2009
3Glioma (Gliomas)
01/2014 - 10/2008
3Hypoxia (Hypoxemia)
01/2014 - 01/2006
2Triple Negative Breast Neoplasms
09/2018 - 09/2012
2Glioblastoma (Glioblastoma Multiforme)
04/2013 - 10/2008
2Adenocarcinoma of Lung
11/2011 - 12/2004
1Circulating Neoplastic Cells
11/2022
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
06/2015
1Hypertension (High Blood Pressure)
07/2014
1Proteinuria
07/2014
1Fatigue
07/2014
1Bone Diseases (Bone Disease)
01/2014
1Cachexia
01/2014
1B-Cell Lymphoma (Lymphoma, B Cell)
01/2014
1Ventricular Tachycardia
01/2014
1Lewis Lung Carcinoma
01/2014
1Pancreatic Neoplasms (Pancreatic Cancer)
06/2012
1Lymphatic Metastasis
06/2011

Drug/Important Bio-Agent (IBA)

11ErbB Receptors (EGF Receptor)IBA
04/2018 - 01/2004
8Biomarkers (Surrogate Marker)IBA
01/2019 - 08/2008
8Gefitinib (Iressa)FDA Link
06/2014 - 01/2004
7Pharmaceutical PreparationsIBA
11/2022 - 08/2005
6Irinotecan (Camptosar)FDA LinkGeneric
05/2008 - 01/2004
5Tyrosine Kinase InhibitorsIBA
04/2018 - 01/2004
4Small Interfering RNA (siRNA)IBA
01/2019 - 01/2011
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2014 - 10/2006
3Phosphotransferases (Kinase)IBA
09/2018 - 06/2014
3Epithelial Cell Adhesion MoleculeIBA
01/2015 - 03/2014
3Complementary DNA (cDNA)IBA
10/2008 - 03/2003
3MicellesIBA
05/2008 - 10/2006
2poly ADP-ribose glycohydrolaseIBA
01/2019 - 11/2013
2Cell-Free Nucleic AcidsIBA
04/2018 - 01/2018
2Trastuzumab (Herceptin)FDA Link
06/2015 - 02/2009
2lenvatinibIBA
07/2014 - 04/2011
2DNA (Deoxyribonucleic Acid)IBA
05/2014 - 01/2014
2Cetuximab (Erbitux)FDA Link
05/2014 - 10/2008
2Therapeutic UsesIBA
01/2014 - 05/2008
2epidermal growth factor receptor VIIIIBA
04/2013 - 10/2008
2EverolimusFDA Link
09/2012 - 12/2011
2Angiogenesis InhibitorsIBA
06/2011 - 01/2006
2Liposomes (Liposome)IBA
12/2010 - 11/2008
2Proteins (Proteins, Gene)FDA Link
12/2010 - 01/2004
2Peptides (Polypeptides)IBA
12/2010 - 11/2008
2Monoclonal AntibodiesIBA
02/2009 - 10/2008
2vandetanib (ZD6474)IBA
01/2006 - 12/2004
2Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2006 - 01/2004
2Tumor Biomarkers (Tumor Markers)IBA
01/2006 - 07/2003
1AntigensIBA
11/2022
1Dual-Specificity PhosphatasesIBA
01/2019
1Alkylating AgentsIBA
01/2019
1Cisplatin (Platino)FDA LinkGeneric
01/2019
1Indicators and Reagents (Reagents)IBA
04/2018
1Blood Proteins (Serum Proteins)IBA
07/2014
1Angiogenic ProteinsIBA
07/2014
1Chemokine CXCL12IBA
07/2014
1Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
07/2014
18- (6- methoxypyridin- 3- yl)- 3- methyl- 1- (4- piperazin- 1- yl- 3- trifluoromethylphenyl)- 1,3- dihydroimidazo(4,5- c)quinolin- 2- oneIBA
06/2014
1TOR Serine-Threonine KinasesIBA
06/2014
1Nuclear Proteins (Protein, Nuclear)IBA
05/2014
1O-(6)-methylguanineIBA
01/2014
1tocilizumab (atlizumab)FDA Link
01/2014
1Temozolomide (Temodar)FDA LinkGeneric
01/2014
1Zoledronic Acid (Zometa)FDA Link
01/2014
1Saline SolutionIBA
01/2014
1Insulin-Like PeptidesIBA
01/2014
1MethyltransferasesIBA
01/2014
1Mevalonic Acid (Mevalonate)IBA
01/2014
1Verapamil (Calan)FDA LinkGeneric
01/2014
1Interleukin-6 (Interleukin 6)IBA
01/2014
1Monomeric GTP-Binding ProteinsIBA
01/2014
1A-Form DNA (A-DNA)IBA
01/2014
1enhanced green fluorescent proteinIBA
04/2013
1AngiopoietinsIBA
04/2013
1Transforming Growth Factors (Transforming Growth Factor)IBA
11/2012
1Epidermal Growth Factor (EGF)IBA
11/2012
1human ERBB2 proteinIBA
09/2012
1Estrogen ReceptorsIBA
09/2012
1ChemokinesIBA
06/2012
1InterleukinsIBA
06/2012
1GemcitabineFDA Link
06/2012
1Interleukin-10 (Interleukin 10)IBA
06/2012
1EnzymesIBA
11/2011
1Heparitin Sulfate (Heparan Sulfate)IBA
11/2011
1ImmunosorbentsIBA
11/2011
1LuciferasesIBA
06/2011
1Vascular Endothelial Growth Factor Receptor-3 (Flt 4)IBA
06/2011
1Sunitinib (Sutent)FDA Link
06/2011

Therapy/Procedure

11Therapeutics
01/2019 - 01/2004
5Drug Therapy (Chemotherapy)
06/2015 - 11/2008
3Radiotherapy
04/2018 - 11/2013
1Neoadjuvant Therapy
09/2018
1Molecular Targeted Therapy
04/2018
1Transplantation
01/2014
1Aftercare (After-Treatment)
06/2011